Why and how to found a (GiveWell) non-profit

We’ve argued against non-profit jobs as an early career move, because many have little impact and you often don’t get good career progression.

However, there’s a certain type of non-profit opportunity that we think is very exciting: start a non-profit focused on implementing an evidence-backed intervention in international development i.e. try to make the next Against Malaria Foundation.


  • There’s lots of evidence-backed interventions that don’t have a well-run, transparent organisation implementing them.
  • Scaling up many of these interventions can be expected to have a big impact.
  • There’s a huge pool of funding for non-profits going after these opportunities, most notably from GiveWell, but also foundations like Gates and CIFF, as well as government aid agencies. These groups would like to fund more non-profits, but can’t find enough that meet their criteria.

We’ve talked about this opportunity for years – see our exploratory career profile on it – and it has become even more pressing recently. The money flowing through GiveWell is growing rapidly, but the pipeline of non-profits isn’t.

GiveWell recently made a post about exactly the sorts of non-profits they’d like to fund:

  1. Charities that implement GiveWell’s priority programs: vitamin A supplementation, immunizations, conditional cash transfers, micronutrient fortification, or even bednets and deworming (since our top charities that focus on the latter two have limited room for more funding).

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