Bonus: Serendipity, weird bets, & cold emails that actually work: Career advice from 16 former guests

How do you navigate a career path when the future of work is uncertain? How important is mentorship versus immediate impact? Is it better to focus on your strengths or on the world’s most pressing problems? Should you specialise deeply or develop a unique combination of skills?

From embracing failure to finding unlikely allies, we bring you 16 diverse perspectives from past guests who’ve found unconventional paths to impact and helped others do the same.

You’ll hear from:

  • Michael Webb on using AI as a career advisor and the human skills AI can’t replace (from episode #161)
  • Holden Karnofsky on kicking ass in whatever you do, and which weird ideas are worth betting on (#109, #110, and #158)
  • Chris Olah on how intersections of particular skills can be a wildly valuable niche (#108)
  • Michelle Hutchinson on understanding what truly motivates you (#75)
  • Benjamin Todd on how to make tough career decisions and deal with rejection (#71 and 80k After Hours)
  • Jeff Sebo on what improv comedy teaches us about doing good in the world (#173)
  • Spencer Greenberg on recognising toxic people who could derail your career (#183)
  • Dean Spears on embracing randomness and serendipity (#186)
  • Karen Levy on finding yourself through travel (#124)
  • Leah Garcés on finding common ground with unlikely allies (#99)
  • Hannah Ritchie on being selective about whose advice you follow (#160)
  • Alex Lawsen on getting good mentorship (80k After Hours)
  • Pardis Sabeti on prioritising physical health (#104)
  • Sarah Eustis-Guthrie on knowing when to pivot from your current path (#207)
  • Danny Hernandez on setting triggers for career decisions (#78)
  • Varsha Venugopal on embracing uncomfortable situations (#113)

Audio engineering: Ben Cordell, Milo McGuire, Simon Monsour, and Dominic Armstrong
Content editing: Katy Moore and Milo McGuire
Transcriptions and web: Katy Moore

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About the show

The 80,000 Hours Podcast features unusually in-depth conversations about the world's most pressing problems and how you can use your career to solve them. We invite guests pursuing a wide range of career paths — from academics and activists to entrepreneurs and policymakers — to analyse the case for and against working on different issues and which approaches are best for solving them.

Get in touch with feedback or guest suggestions by emailing [email protected].

What should I listen to first?

We've carefully selected 10 episodes we think it could make sense to listen to first, on a separate podcast feed:

Check out 'Effective Altruism: An Introduction'

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If you're new, see the podcast homepage for ideas on where to start, or browse our full episode archive.